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Severe maternal morbidity, in plain words

A list of 21 life-threatening events at delivery. It affects roughly one to two hospital deliveries in a hundred, and most of that is blood transfusion.

You will meet the phrase "severe maternal morbidity" in the news. It is a technical term, not a diagnosis, and knowing what it contains changes how it reads.

CDC's definition: Severe maternal morbidity (SMM) includes unexpected outcomes of labor and delivery that can result in significant short- or long-term health consequences. CDC finds it in hospital records using a set of diagnosis codes: These 21 indicators and corresponding ICD codes can identify delivery hospitalizations with SMM using administrative data starting in October 2015.

The single most important thing to know. The measure is dominated by blood transfusion. That is why researchers routinely report it twice, with and without transfusion counted, and the two numbers differ by roughly a factor of two.

Study and databasePeriodCounting rulePer 10,000 hospital deliveries
National Inpatient Sample and state databases2012 to 2019Transfusion excluded69.5 to 79.7
Nationwide Readmissions Database2016 to 2022Transfusion excludedabout 70 to about 100
Nationwide Readmissions Database2016 to 2022Transfusion includedabout 150 to about 220
Premier all-payer database2008 to 2021Transfusion included146.8 to 179.8

Put in words: roughly 1.5 to 2 hospital deliveries in every 100 when transfusion is counted, and roughly 0.7 to 1 in every 100 when it is not. All three studies show the same direction of travel.

And alongside that rise, in the same Premier data: deaths during delivery-related hospitalizations fell from 10.6 per 100,000 in early 2008 to 4.6 per 100,000 in late 2021. Severe events rose; deaths fell.

Treat this measure with some cautionTwo of the people most responsible for developing it wrote in 2026 that despite 50 years of effort by national, international, and professional organizations, determining the ideal SMM measure remains a work in progress. There is also a technical break in the record: the US changed diagnosis coding systems in October 2015, and one analysis showed the change alone moved five of twenty indicator rates. Any trend line crossing that date carries that problem with it.
Say this out loud

"Does that statistic include blood transfusion, or not?"

"Which of these things would actually apply to me?"

Where this comes from:
502. Centers for Disease Control and Prevention. Severe maternal morbidity [Internet]. Atlanta (GA): National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health; page dated 15 May 2024.
498. Hirai AH, Owens PL, Reid LD, Vladutiu CJ, Main EK. Trends in severe maternal morbidity in the US across the transition to ICD-10-CM/PCS from 2012-2019. JAMA Netw Open. 2022;5(7):e2222966.
499. Kawakita T, Jones SA, Furukawa N, Saade G. Contribution of comorbidities and pregnancy complications to severe maternal morbidity in the United States. Obstet Gynecol. 2026;147(6):877-84.
500. Fink DA, Kilday D, Cao Z, Larson K, Smith A, Lipkin C, et al. Trends in maternal mortality and severe maternal morbidity during delivery-related hospitalizations in the United States, 2008 to 2021. JAMA Netw Open. 2023;6(6):e2317641.
501. Main EK, Creanga AA. Measuring severe maternal morbidity: current practices, challenges, and opportunities. Obstet Gynecol. 2026;147(6):806-16.

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