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Evidence Library · The numbers

A first baby and a later baby are different decisions

In the English data, planning a home birth carried a higher rate of serious problems for a first baby and a slightly lower one for a later baby. And only 12% of those problems were deaths.

This is the single most important thing in this stage. If you take away one idea, take this one.

The Birthplace in England study followed 64,538 healthy women with low-risk pregnancies who booked a birth in one of four settings, and counted a combined measure of serious problems for the baby. Here are the whole-group results, per 1,000 births, with the counts.

Planned place of birthAll womenFirst babyLater baby
Hospital labor unit4.4 (81/19,551)5.3 (52/10,541)3.3 (29/8,980)
Home4.2 (70/16,553)9.3 (39/4,488)2.3 (31/12,050)
Freestanding midwifery unit3.5 (41/11,199)4.5 (24/5,158)2.7 (17/6,025)
Midwifery unit at a hospital3.6 (58/16,524)4.7 (38/8,256)2.4 (20/8,234)

One note about the arithmetic, before you check it. Birthplace sampled hospital labor units at random rather than counting all of them, and it publishes rates weighted for that design rather than simple proportions. So the rate in each cell is not the two numbers beside it divided out: 39 out of 4,488 is printed as 9.3 per 1,000, not 8.7. Both the counts and the rates are as published, and this is true of every Birthplace figure in this stage.

Read the middle column and the right-hand column separately, because they point in opposite directions.

For a first baby, planning a home birth carried 9.3 serious problems per 1,000 against 5.3 in a hospital labor unit, an adjusted odds ratio of 1.75 (95% confidence interval 1.07 to 2.86). Among first-time women with no complicating conditions at all when labor care started, it was 9.5 against 3.5 per 1,000, an adjusted odds ratio of 2.80 (1.59 to 4.92). NICE puts the difference in its own words: planning birth at home is associated with an overall small increase in the risk of a baby having a serious medical problem (about 4 more per 1,000 births) compared with planning birth in other settings.

For a later baby, planning a home birth carried 2.3 per 1,000 against 3.3 in a hospital labor unit, with an adjusted odds ratio of 0.72 (0.41 to 1.27). That runs the other way, and it did not reach statistical significance in either direction. NICE's own advice reflects this split exactly, and it is worth quoting because it is a national guideline recommending home birth for one group and warning about it for another: Advise low-risk multiparous women that planning to give birth at home or in a midwifery-led unit (freestanding or alongside) is associated with a lower rate of interventions and the outcome for the baby is no different compared with an obstetric unit. And for first babies: Explain that if they plan birth at home, there is a small increase in the risk of an adverse outcome for the baby.

Now the second half of this topic, which is the part most often left out.

The phrase "serious medical problem" in that study does not mean death. NICE published the breakdown of what the 255 events actually were.

What happenedBabies affectedShare of all the problems counted
Neonatal encephalopathy102 / 63,955 (1.6 per 1,000)40%
Meconium aspiration syndrome86 / 63,955 (1.3 per 1,000)34%
Brachial plexus injury24 / 63,955 (0.38 per 1,000)9%
Death in the first week18 / 64,292 (0.28 per 1,000)7%
Stillbirth after labor care started14 / 64,535 (0.22 per 1,000)5%
Broken collarbone or arm bone11 / 63,955 (0.17 per 1,000)4%
12%
Were deaths
Stillbirth plus first-week death
40%
Encephalopathy
The largest single component
34%
Meconium aspiration
The second largest
The correction that has to be made out loudIf you read "9.3 per 1,000" and heard "9.3 babies per 1,000 die," you read it the way almost everyone does. Only 12% of those events were deaths. About three quarters of them were neonatal encephalopathy and meconium aspiration syndrome, which are serious and can leave lasting harm, and which are not the same thing as a death. A guide that let you carry away the wrong version of this number would have failed you, and so would one that hid the number.
Say this, and expect a good attendant to welcome it"Is this my first birth? Does that change your advice?"
"When you say the risk of a serious problem, do you mean death, or do you mean something broader? What is in that count?"
"What are the numbers per 1,000 for a woman like me, having the baby I am having?"
Where this comes from:
641. Birthplace in England Collaborative Group; Brocklehurst P, Hardy P, Hollowell J, Linsell L, Macfarlane A, et al. Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study. BMJ. 2011;343:d7400.
642. National Institute for Health and Care Excellence. Intrapartum care. NICE guideline NG235. Published 29 September 2023; last updated 9 June 2026. https://www.nice.org.uk/guidance/ng235

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