What pregnancy complications result from donated eggs?

A study published in the American Journal of Obstetrics and Gynecology revealed complications associated with pregnancy with a maternal age of 44 and over. The study involved about 80,000 women in which about 175 women aged 45 and over  gave birth, many of these births resulted from the use of egg donors.

These older women had a higher incidence of maternal complications than younger counterparts. About 17% of the older women were diagnosed with gestational diabetes as compared to only 6% of younger women. Higher blood pressure was a problem for 9% of older women but only 3% of younger pregnant participants. The rate of C-section also doubled in the older population.

In addition to complications during pregnancy, older women presented with an increased rate of complications after birth including fever, excessive bleeding, extended stays in the hospital and more occurrences of intensive care. Infants born to older mothers even showed decreased health with metabolic problems reported in 4% of the newborns born to older mothers compared to 2% born to younger mothers.



The risks of using Cytotec (misoprostol) for labor induction

Serena Williams recently revealed that her labor was induced, she developed “fetal distress,” needed a cesarean delivery and subsequently developed a major complication called “pulmonary embolism”. She did not reveal how her labor was being induced, but chances are that it was Cytotec (misoprostol).

Cytotec is a medication created to reduce the incidence of gastric ulcers. It was not made to induce labor, yet many doctors give it to their patients in addition to the standard induction drug, Pitocin. In the black box warning for the drug (the strictest warning put in the labeling of prescription drugs or drug products by the Food and Drug Administration), it advises against pregnant women taking the drug at all. In fact, it states:

“SPECIAL NOTE FOR WOMEN: Cytotec may cause abortion (sometimes incomplete), premature labor, or birth defects if given to pregnant women.” The black box warning also states that “vaginal administration of Cytotec, outside of its approved indication, has been used as a cervical ripening agent, for the induction of labor” and that it causes a higher risk for a cesarean section.

Serena Williams’ medical history of blood clots, embolisms, and hematomas, was well established before her labor and delivery as was evidenced in her HBO TV series, Being Serena. Her now husband, Alexis Ohanian explained in one episode: “The C-section was low on our wish list because of her history of blood clots. Any surgery that Serena has is potentially life-threatening.”

Not only was Serena induced which has a high rate of C-section, but she had to repeatedly ask for further testing to rule out blood clots. When she couldn’t breathe after getting out of bed the day after delivering her baby, she was given an oxygen mask which caused her to cough so hard, she opened up her cesarean section stitches and had to be taken back to the operating room to repair it. She was given a test (doesn’t specify which one) to see if she had blood clots and was told she didn’t have any.

That’s when she insisted on a CAT scan with contrast dye. It was then that the pulmonary embolism was discovered as well as other blood clots in her legs. She ended up needing three surgeries in all, including one to place a filter to temporarily prevent blood clots from reaching her heart.

Out of 3,859 people reported to have side effects when taking Cytotec, 26 people had a pulmonary embolism. Pregnancy in and of itself is risky as your blood volume increases and any existing medical conditions are affected. Being induced raises the risk of having a cesarean section so if you have a history of blood clots, you should avoid being induced. Any surgery has a risk of complications but that risk is exponentially higher if you have a history of blood clots or embolism.



Misperceptions about what causes a miscarriage

A miscarriage is the loss of a pregnancy before 20 weeks and happens in over 50% of all pregnancies, most of them early in pregnancy. Studies have shown that over 4 in 5 miscarriages are due to chromosomal anomalies and unrelated to other conditions.

This study published online in May in the Obstetrics & Gynecology journal called “A National Survey on Public Perceptions of Miscarriage” asked about perceptions about miscarriage. Not surprisingly, most who answered the questionnaire have many misconceptions about miscarriage.

Respondents to the survey erroneously believed that miscarriage is a rare complication of pregnancy, with the majority believing that it occurred in 5% or less of all pregnancies (it actually happens in over 50% of all pregnancies).

There were also widespread misperceptions about causes of miscarriage (the causes are often unknown though chromosomal anomalies are frequent).

Those who had experienced a miscarriage frequently felt guilty, isolated, and alone. Identifying a potential cause of the miscarriage may have an effect on patients’ psychological and emotional responses.